Thermal Cyclers (also known as DNA cyclers, thermo cyclers, PCR machines, or DNA amplifiers) are used to amplify segments of DNA via the polymerase chain reaction and are essential for labs that rely on molecular biology. Their use is crucial for applications such as detection and diagnosis of infectious diseases and hereditary diseases, DNA cloning for sequencing, and DNA profiling. Thermal Cyclers provide a thermally controlled environment for DNA samples that are necessary during temperature cycling. Because the process relies heavily on precise temperature control, it is vital that this equipment has proper thermal management. Because they required the best possible thermal design for their newest Thermal Cycler design, Bio-Rad contacted Aavid, Thermal Division of Boyd Corporation.